P67葉奕棟

CURRICULUM VITAE September 2008 Yicktung Tony Ip
Personal information
Date of birth: June 3rd, 1959
Place of birth: Hong Kong
Citizenship: USA, since 2000
Address: Program in Molecular Medicine,
University of Massachusetts Medical School
373 Plantation Street, Suite 109, Worcester, MA 01605

Education
1984-89 Ph.D. (Biochemistry) University of Iowa, USA.
(Advisor: Dr. Roger Chalkley)
1980-84 B.S. (Pharmacy, P67) National Defense Medical Center, Taipei, ROC.

Professional positions
2000-present Associate Professor, University of Massachusetts Medical School (with tenure, 2002)
1994-2000 Assistant Professor, University of Massachusetts Medical School
1990-1994 Postdoctoral Fellow, University of California San Diego (Advisor: Dr. Michael Levine)
1989-1990 Postdgraduate Fellow, Vanderbilt University (Advisor Dr. Roger Chalkley)

Awards
7/96-6/01 Scholar Award, Leukemia and Lymphoma Society of America
6/91-5/94 Hoffmann-La Roche Postdoctoral Fellow of the Life Sciences Research Foundation

Present Grant Support
1. NIH R01 GM53269-13 Molecular mechanisms of Drosophila innate immune response.
2. NIH R21 DK75545-02 Host-microbe interaction in the Drosophila gut.
3. Worcester Foundation for Biomedical Research, Research Grant,
Intestinal stem cell regulation and tissue repair in Drosophila

Representative publications (total 55 research and review articles)
Ip, Y. T., Jackson, V., Meier, J., and Chalkley, R. (1988) The separation of transcriptionally engaged genes. J. Biol. Chem. 263: 14044-14052.
Ip, Y. T., Reach, M., Engstrom, Y., Kadalayil, L., Cai, H., Gonzalez-Crespo, S., Tatei, K., and Levine, L. (1993) Dif, a dorsal-related gene that mediates an immune response in Drosophila. Cell 75: 753-763.
Sluss, H. K., Han, Z., Berette, T., Goberdhan, D. C. I., Wilson, C., Davis, R. J., and Ip, Y. T. (1996) A JNK signal transduction pathway that mediates morphogenesis and an immune response in Drosophila. Genes & Development 10: 2745-2758.
Hu, X., Yagi, Y., Tanji, T., Zhou, S., and Ip, Y.T. (2004) Multimerization and interaction of Toll and Spatzle in Drosophila. Proc. Natl. Acad. Sci. USA. 101: 9369-9374.
Tanji, T., Hu, X., Weber, A. and Ip , Y.T. (2007) Toll and IMD pathways synergistically activate innate immune response in Drosophila. Mol. Cell. Biol. 27: 4578-4583.

Personnel Trained
Postdoctoral fellows trained: 9
Ph.D. students trained: 5